| Name | Expression | M. W. | Functions | Other names | Family |
|---|---|---|---|---|---|
| CD51 | platelets, megakaryocytes | 125,24 dimer | av integrin, associates with CD61, binds vitronectin, von Willebrand factor, fibrinogen and thrombospondin | vitronectin receptor | |
| CD52 | thymocytes, T cells, B cells (not plasma cells), monocytes, granulocytes | 21-28 | unknown, target for antibodies used therapeutically to deplete T cells | CAMPATH-1 | |
| CD53 | leukocytes | 35-42 | unknown | MRC OX44 | tetraspanning membrane protein |
| CD54 | hematopoietic and non-hematopoietic cells | 85-110 | InterCellular Adhesion Molecule, (ICAM)-1 binds CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1) integrins, receptor for rhinovirus | ICAM-1 | IgSF |
| CD55 | hematopoietic and non-hematopoietic cells | 60-70 | Decay Accelerating Factor (DAF), binds C3b, disassembles C3/C5 convertase | DAF | CCP superfamily |
| CD56 | NK cells | 175-185 | isoform of Neural Cell Adhesion Molecule (NCAM), adhesion molecule | NKH-1 | IgSF |
| CD57 | NK cells subsets of T cells, B cells and monocytes | oligosaccharide, found on many cell surface glycoproteins | HNK-1, Leu-7 | ||
| CD58 | hematopoietic and non-hematopoietic cells | 55-70 | Leukocyte Function-associated Antigen-3 (LFA-3), binds CD2, adhesion molecule | LFA-3 | IgSF |
| CD59 | hematopoietic and non-hematopoietic cells | 19 | binds comlement components C8 and C9, blocks assembly of membrane attack complex | Protectin, Mac inhibitor | |
| CD60 | T cell subsets, platelets, monocytes | oligosaccharide present on gangliosides | |||
| CD61 | platelets, megakaryocytes, macrophages | 105 | integrin b3 subunit, associates with CD41 (GPIIb/IIIa) or CD51 (vitronectin receptor) | ||
| CD62E | endothelium | 140 | endothelium leukocyte adhesion molecule (ELAM), bindssialyl-Lewis x, mediates rolling interaction of neutrophils on endothelium | ELAM-1, E-selectin | C type lectin |
| CD62L | B cells, T cells, monocytes, NK cells | 150 | leukocyte adhesion molecule (LAM), binds CD34, GlyCAM, mediates rolling interactions with endothelium | LAM-1, L-selectin, LECAM-1 | C type lectin |
| CD62P | platelets, megakaryocytes, endothelium | 140 | adhesion molecule, binds sialyl Lewis x, mediates interaction of platelets with neutrophils, monocytes and rolling interaction of neutrophils on endothelium | P-selectin, PADGEM | C type lectin |
| CD63 | activated platelets, monocytes, macrophages | 53 | unknown, is lysosomal membrane protein translocated to cell surface after activation | tetraspanning membrane protein | |
| CD64 | monocytes, macrophages | 72 | hign affinity receptor for IgG | FcgRI | IgSF |
| CD65 | myeloid cells | oligosaccharide component of a ceramide dodecasaccharide | |||
| CD65s | Ceramide dodecasaccharide 4c | ||||
| CD66a | neutrophils | 160-180 | unknown, member of carcinoembryonic antigen (CEA) family (see below) | biliary glycoprotein-1 (BGP-1) | IgSF |
| CD66b | granulocytes | 95-100 | unknown, member of carcinoembryonic antigen (CEA) family | previously CD67 | IgSF |
| CD66c | neutrophils, colon carcinoma | 90 | unknown, member of carcinoembryonic antigen (CEA) family | Nonspecific Crossreacting Antigen (NCA) | IgSF |
| CD66d | neutrophils | 30 | unknown, member of carcinoembryonic antigen (CEA) family | IgSF | |
| CD66e | adult colon epithelium, colon carcinoma | 180-200 | unknown, member of carcinoembryonic antigen (CEA) family | CarcinoEmbryonic Antigen (CEA) | IgSF |
| CD66f | Pregnancy specific glycoprotein | ||||
| CD68 | monocytes, macrophages, neutrophils, basophils, large lymphocytes | 110 | unknown | macrosialin | |
| CD69 | activated B cells, activated T cells, activated macrophages, activated NK cells | 28, 32 homo-dimer | unknown, early activation antigen | Activation Inducer Molecule (AIM) | |
| CD70 | activated B cells, activated T cells, macrophages | 75,95,170 | unknown | Ki-24 | |
| CD71 | activated leukocytes | 90-95 homo-dimer | transferrin receptor | T9 | |
| CD72 | B cells | 42 homo-dimer | unknown, ligand for CD5 | Lyb-2 | C type lectin |
| CD73 | B cell subsets, T cell subsets | 69 | ecto-5?-nucleotidase, dephosphorylates nucleotides to allow nucleoside uptake | ||
| CD74 | B cells, macrophages, monocytes, MHC class II positive cells | 33,35,41,43 (alternate initiation and splicing) | MHC class II associated Invariant chain | Ii, Ig | |
| CDw75 | mature B cells, T cell subsets | unknown, possibly oligosaccharide, dependent on sialylation | |||
| CDw76 | mature B cells, T cell subsets | unknown, possibly oligosaccharide, dependent on sialylation | |||
| CD77 | germinal center B cells | unknown, | Gb3, Pk blood group | ||
| CDw78 | B cells | unknown | Ba | ||
| CD79a, CD79b |
B cells | a: 32-33 b: 37-39 |
components of B cell antigen receptor analogous to CD3, required for cell surface expression and signal transduction | Iga, Igb | IgSF |
| CD80 | B cell subset | 60 | costimulator, ligand for CD28 and CTLA-4 | B7 (now B7-1), BB1 | IgSF |
| CD81 | lymphocytes | 26 | associates with CD19, CD21 to form B cell coreceptor | Target of AntiProliferative Antibody (TAPA-1) | tetraspanning membrane protein |
| CD82 | leukocytes | 50-53 | unknown | R2 | tetraspanning membrane protein |
| CD83 | Activated B cells, activated T cells, circulating dendritic cells (veil cells) | 43 | HB15 | ||
| CDw84 | monocytes, platelets, circulating B cells | 73 | GR6 | ||
| CD85 | monocytes, circulating B cells | 120, 83 | GR4 | ||
| CD86 | monocytes, activated B cells | 80 | FUN-1, GR65 | ||
| CD87 | granulocytes, monocytes, macrophages, activated T cells | 50-65 | Urokinase plasminogen activator receptor | UPA-R | |
| CD88 | polymorphonuclear leukocytes, macrophages, mast cells | 40 | Receptor for complement component C5a | C5aR | rhodopsin superfamily |
| CD89 | monocytes, macrophages, granulocytes, neutrophils, B cell subsets, T cell subsets | 50-70 | IgA receptor | FcaR | IgSF |
| CD90 | CD34+ prothymocytes (human) thymocytes, T cells (mouse) | 18 | unknown | Thy-1 | IgSF |
| CD91 | monocytes | 600 | a2 macroglobulin receptor | unknown | |
| CDw92 | neutrophils, monocytes, platelets, endothelium | 70 | unknown | GR9 | |
| CD93 | neutrophils, monocytes, endothelium | 120 | unknown | GR11 | |
| CD94 | T cell subsets, NK cells | 43 | unknown | KP43 | |
| CD95 | wide variety of cell lines in vivodistribution uncertain | 43 | binds TNF-like ligand, induces apoptosis | Apo-1, Fas | NGF receptor superfamily |
| CD96 | activated T cells | 160 | Unknown | T cell ACTivation Increased Late Expression (TACTILE) | |
| CD97 | activated cells | 74, 80, 90 | unknown | GR1 | |
| CD98 | T cells, B cells, NK cells, granulocytes, all human cell lines | 80, 40 | unknown | 4F2 | |
| CD99 | Peripheral blood lymphocytes, thymocytes | 32 | Unknown | MIC2, E2 | |
| CD100 | Broad expression on haematopoietic cells | 150 | unknown | GR3 |
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